| ALL
STEROIDOGENIC TISSUES |
| STEROID
SYNTHESIS |
| CHOLESTEROL (C27) |
|
|
|
| minus side |
||
| chain |
||
| + 20-keto |
| GONADS |
| PREGNENOLONE
(C21) |
| + 3-keto |
| + 17-OH |
| desmolase |
| sulfotransferase |
|
|
|
| DEHYDROEPIANDROSTERONE” |
||
| ’’DHEA” |
||
| 17-OH
PREGNENOLONE |
| PROGESTERONE |
| + 3-keto |
| + 17-OH |
| + 21-OH |
| + 3-keto |
| desmolase |
| + 11-OH |
| 17-OH
PROGESTERONE |
| ANDROSTENEDIONE (C19) |
| CORTICOSTERONE |
| + 21-OH |
| TESTOSTERONE |
| aromatase |
| +
18-ALDEHYDE |
| + 11-OH |
| +3-keto |
| ESTRONE |
| aromatase |
| ALDOSTERONE (C21) |
| CORTISOL
(C21) |
| ADRENAL
CORTEX |
| DIHYDROTESTOSTERONE
(C19) |
| ESTRADIOL
(C19) |