Normal
implantation site
Implantation
Ectopic sites
of implantation
| Normal implantation: Larsen, WI, Human Embryology, 3rd
ed., Churchill Livingston, NY (2001), p. 22 |
|
| Ectopic sites: Carlson 3rd ed., p. 60 |
|
| Endometrium: |
|
| Anatomy of uterus. |
|
| Blastocyst 0.1 - 0.2mm
diameter. Mucosa 5mm, Slit-like
Lumen of uterus 1mm anterior to posterior |
|
| Fundus - Dorsal wall |
|
| More than 3/4 (78%)
fertilized oocytes do not reach term. |
|
| 62% conceptions lost in
first 12 weeks. |
|
| Ectopic (1%) 0.25-1.4% of
all pregnancies - of those 95% are tubal |
|
| Tubal - pelvic
inflammatory disease; rupture of
wall partly because there are no uterine NK cells as there are in the
endometrium to induce apoptosis in trophoblast that invades too deep |
|
| cervical = placenta
praevia |