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| The
Central Mechanism of Kidney Development is |
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Conversion of |
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| Mesenchyme
into Epithelia |
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| • | MET: Kidney and
Testis |
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| • | EMT:
Neural Crest, Endocardial cushion, Carcinoma, Damage to Tubules. |
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| Mesenchyme Epithelia |
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| Motile, migratory Sessile |
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| Few Cellular Contacts Tightly Adherent |
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| NCAM E-cadherin,
ZO-1 |
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| Diffuse Extracellular Matrix Localized Matrix (basal) |
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| Collagen I III Collagen IV |
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| Polarity by leading edge Polarity Apical-Basal |
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| Vimentin IF Cytokeratin IF |
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| CYTOKINE |
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| WNT |
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