Respiratory embryology

Lung histology

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Lung Histology: Conducting zone

Pulmonary Histology

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Laryngeal development

Epithelium of the larynx

Trachea

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Bronchi/lungs

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Branching morphogenesis

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Lung Maturation

Early pseudoglandular 8 wk

Mid Pseudoglandular 13 wk

Late pseudoglandular-16 weeks

Mid-canalicular - 22 weeks

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Congenital malformations

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Breathing exercise

Causes of Lung hypoplasia – diminished lung development

Expansion of the lung activates a transcriptional program.

RDS-Respiratory distress syndrome

Pulmonary vasculature

Molecular determinants of branching morphogenesis

Branching determinants

FGF-fibroblast growth factor

Factors in branching morphogenesis

Branching parameters

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