Inhibition of FGF10 by
epithelial Shh; BMP4 also needed,
Shh induces mesenchymal proliferation and differentiation – zone growth stabilized.
Shh induces mesenchymal proliferation and differentiation – zone growth stabilized.
Shh effect is localized, FGF10 less inhibited
Greater stabilization by mesenchymal differentiation, extracellular matrix and cell to matrix adhesion
