| Signal
transduction in nociceptors |
|
|
| VR1/VRL-1 |
|
| TRPV1 |
|
| ASIC |
|
|
| CMR1 |
|
| TRPM8 |
|
| ENaC/DEG |
| TRP |
|
|
|
|
| VR1 –
vanilloid receptor 1 or TRPV1 |
|||
| CMR1 – cold
and menthol activated receptor 1 or TRPM8 |
|||
| ASIC – acid
sensing ion channel |
|||
| Degenerin family |
|||
|
|
| Modified from
Julius and |
|
| Basbaum, 2001 |
|