Fear conditioning is a tool for investigating neural
substrates of emotion.
Fear conditioning is a process in which a neutral
stimulus (conditioned stimulus, CS) is paired with an
aversive stimulus (unconditioned stimulus, US), so that
the CS comes to predict an aversive outcome, eliciting
fear behaviors even in the absence of the US.
Fear conditioning can be found in a large range of
animals, from rodents to rabbits to humans.
As early as the 1920s, fear conditioning was
demonstrated in infants.  A white rat presented to an
infant does not innately elicit fear, but pairing the rat with
an aversive noise, produces crying and attempts to crawl
away, even when the rat was presented without the
noise.