Molecular mechanisms underlying regeneration:
1.
Vaccination to combat myelin
Therapeutic approach:
stimulate animals’ own
immune system by injection of spinal cord homogenate
to generate polyclonal antibodies
that block the inhibitory factors on myelin / adult CNS cells.
Practicalities of immunizing humans with myelin?
Huang et al., 1999, Neuron 24: 639;
See also work of M. Schwartz