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REACTIONS TO
INJURY WITHIN THE NEURON:
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Immediately -
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1. Synaptic transmission off
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2. Cut ends pull apart and seal up, and
swell,
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due to axonal
transport in both directions
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Hours
later -
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Synaptic
terminal degenerates - accumulation of NF, vesicles.
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Astroglia
surround terminal normally;
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after axotomy, astroglia interpose
between terminal and target
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and cause terminal to be pulled
away from postsynaptic cell.
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