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Molecular mechanisms underlying regeneration
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4. Increase (good) microglia in eye by
stabbing lens*
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*or by a
macrophage activator
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Macrophages
activated;
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retinal axons regenerate
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Macrophage-derived
proteins < 30 kD are growth-
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promoting
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Yin…and Benowitz, 2003, J.
Neurosci. 15: 2284
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