| Narcolepsy: summary |
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| Hypothetical Effect of Blunted Hcrt
Activation: |
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| 1. | Monoaminergic Nuclei of the Brainstem: induce |
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| cataplexy. |
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| 2. | Cholinergic Brainstem and Basal Forebrain: cause |
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| sleepiness associated with narcolepsy. |
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| 3. | Dense Hcrt Projections to the
Suprachiasmatic Nucleus: |
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| reduced amplitude of circadian sleep rhythms, and |
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| thereby increased sleepiness during the day and |
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| interrupted sleep at night. |
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