Central Representation of Touch

Mechanosensation

Slide 3

Slide 4

Somatotopic Organization

Wilder Penfield

2 Point Discrimination

CNS neurons have receptive fields

RF ProxDist

RF ProxDist

RF ProxDist

AnimalS1’s

Slide 13

RF simple

RF + gradient

Slide 16

RF complex

RF gradent w/out & with

Braile 3-D

Braile w &w/O inhib

Receptive Field Structure

Directional tuning

Inhibition-distal

How is information from different mechanoreceptors represented in primary somatic sensory cortex?

RF hands

Texture

Texture code:

MonkeyStriateNissl_LP

Monkey Nissl_hP

Monkey Nissl_hP

Slide 31

Merzenich

Slide 33

Slide 34

Summary

Slide 36

Slide 37