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| Three
neural signals for the induction |
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| of
postsynaptic differentiation |
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| • | Agrin:
aggregation of receptors in the |
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| muscle membrane |
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| • | Neuregulin:
by upregulation of ACh-R |
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| expression in
sub-synaptic nuclei |
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| • | ACh/neural
activity: downregulation of |
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| ACh-R expression
in extra-synaptic nuclei |
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