|
|
|
|
| motor neur. skel. mus. |
|||
| ANS, esp.
parasympath. |
|||
| n. basalis of Meynert |
|||
| presynaptic
modulator |
|||
| O |
|
|
| myasthenia gravis |
|
| Alzheimer’s |
|
| CAT |
| acetyl CoA + choline |
| CH3-C-O-CH2-CH2-N+-(CH3)3
+ CoA |
| acetylcholine |
| HO- |
|
|
| substan. nigra caudate n. |
|
| midbrain limbic system |
|
|
|
|
| Parkinson’s |
||
| drug addiction |
||
| schizophrenia |
||
| AAAD |
| TH |
| tyrosine + O2 |
| L-DOPA |
| HO- |
| -CH2-CH2-NH2 |
| dopamine |
| OH |
| HO- |
|
|
| sympathetic
endings |
|
| locus coeruleus |
|
| DBH |
| dopamine |
| HO- |
| -CH-CH2-NH2 |
| depression |
| norepinephrine |
| OH |
| HO- |
|
|
| adrenal medulla |
|
| (neurohormone) |
|
| PNMT |
| norepinephrine |
| HO- |
| -CH-CH2-NH-CH3 |
| epinephrine |
| raphé n. |
| depression |
| TrH |
| AAAD |
| -CH2-CH2-NH2 |
| tryptophan + O2 |
| 5-HTP |
| serotonin |
| N |
| glutamate |
|
|
| major excitatory
transmitter |
|
| in brain |
|
| stroke |
| GAD |
|
|
| major inhibitory
transmitter |
|
| in brain |
|
| epilepsy |
| gamma-amino butyric acid
(GABA) |
| glutamate |
| glycine |
|
|
| major inhibitory
transmitter |
|
| in spinal cord |
|