|
|
|
| Molecular
mechanisms underlying regeneration: |
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| 7. (cont.) Molecular identification of 3
myelin-associated |
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| factors, their common receptor and
co-receptor |
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|
|
|
|
|
|
|
|
|
| The
three known myelin proteins: |
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| MAG (myelin-associated glycoprotein) |
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| NOGO |
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| OMGp (Oligodendrocyte myelin glycoprotein) |
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| interact
with the Nogo Receptor (NgR), |
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| which,
in turn, interacts with |
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| the
P75 receptor, a known “negative” |
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| receptor,
leading downstream to |
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| growth
inhibition |
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