Evidence for Hormonal Effects
on Mood in Affective Illness
1.
Unipolar syndromes occur during drops in
estrogen/progesterone:
•
Premenstrual
•
Postpartum
•
Perimenopausal
2.
Iatrogenic affective symptoms:
•
HRT lowers depression scores.
•
Affective symptoms have been associated with
OCP and GnRH agonists.
Women and Bipolar Disorder