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| Platelets Used as a Serotonin Neuron Model |
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| In
Studies of Major Depression |
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| • | Lots
of serotonin-related abnormalities. |
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| • | Serotonin
uptake low. |
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| • | Serotonin
transporter sites are fewer. |
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| • | More
5-HT2A receptors in association with suicidal acts. |
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| • | 5-HT2A
signal transduction is blunted in suicidal cases. |
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| • | Possible
link to increased risk of death from myocardial |
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| infarction
in major depression. |
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