SUCCESSFUL TREATMENT
NORMALIZES HPA STRESS SYSTEM
OVER-ACTIVITY IN DEPRESSION
•
HPA overactivity may be reduced by successful
antidepressant treatment
•
Reduced HPA activity may result in more
hippocampal 5-HT1A receptors and perhaps
hippocampal growth.
•
Reduction in CRH may reduce the depression
symptoms due to CRH itself.