n Cortisol hypersecretion occurs in severely depressed and suicidal children/adol requiring hosp., and during recurrence of MDD. n Increased urinary catecholamines and decreased urinary cortiosol levels seen in children/adolescents with PTSD n Autistic pt’s:  decreased activity in serotonergic pathways, and alterations in DA system, GH responses and abnormal stress responses of HPA axis.
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